Prevalence of metabolic syndrome (MS) in recent decades has become an epidemic. The frequency of this pathology in the adult population in developed countries is not less than 10–20% of the adult population. With the metabolic syndrome in their practice, doctors of many specialties encounter it — cardiologists, endocrinologists, general practitioners, and gynecologists.

What is metabolic syndrome?

Metabolic syndrome is a cluster of conditions — including elevated blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol levels — that occur together and increase the risk of heart disease, stroke, and type II diabetes. In recent years, the validity of using Metformin in this pathology has been increasingly discussed.

Metformin's role

Metformin has attracted renewed attention since the description of metabolic syndrome. Having been used to treat diabetes for more than 40 years, its established safety profile and effects on insulin sensitivity make it a relevant option in addressing the underlying metabolic disturbances seen in MS. The medication is relevant across cardiology, endocrinology, and even pediatrics, where early intervention in metabolic dysfunction is increasingly recognized.

Clinical relevance across specialties

Because metabolic syndrome sits at the intersection of multiple organ systems, its management draws on expertise from several fields:

• Cardiology — addressing the elevated cardiovascular risk that accompanies MS.
• Endocrinology — managing the hormonal and glucose dysregulation central to the syndrome.
• Pediatrics — responding to the rising prevalence of obesity and early metabolic dysfunction in younger populations.