Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine in amoebic liver abscess Uptodate hydroxychloroquine Can you stop plaquenil right away Nobody really knows how to manage healthies who have a few "lupus anticoagulants" but it's news to me that plaquenil hydroxychloroquine would be a first-line Rx. It's not an innocuous medicine and is strong stuff even if you do have discoid lupus. And many folks have positive anti-nuclear antibodies but no sign of lupus. Read more. Oct 28, 2018 Your doctor may say you have lupus if you have at least four of 11 signs of the disease that are laid out by experts at the American College of Rheumatology Butterfly-shaped rash. Raised red patches on your skin. You're sensitive to light. Ulcers in your mouth or nose. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system. Unfortunately you can't tell it to attack just the germs so you suppress all of its function to spare your healthy tissue- in your husband's case, his eyes, mouth, throat. NOTE Plaquinil and hydroxychloroquine are essentially the same drug. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Can plaquenil change ana Healthboards - Immune & Autoimmune - Lupus Negative ANA Lupus?, What are the 11 signs of lupus? - WebMD Quitting plaquenilChloroquine tablet 500mgHow to take chloroquine phosphate 500 mgDiagnosis code for plaquenil therapyChloroquine pharmacological class FYI, a person with Lupus can have a negative ANA result; one example with the URL; Glojer, PM Welcome Jackie Lu. Yes I have had a positive Ana test in 2003 0 and just this year had two negative Ana, one while on plaquenil and one after being off plaquenil for 3weeks. Can ANA go away & Lupus Stay? - Lupus - MedHelp. Do either hydroxychol/Plaquenil put you at risk for greater.. Can plaquenil change blood test results?. Apr 26, 2007 Can a person’s ANA fluctuate between positive and negative when they are sick/not sick? Answer ANA tests can vary in the titer and often times ;ow titer ANA blood tests often turn negative. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin. Loss of appetite. Abdominal bloating. Upset stomach. A lot of people have less than 4, or as in my case, more than 4 but spread out over much more than 5 years. So it's very possible for plaquenil to do good without you being considered to have Lupus. I went on plaquenil in 2004 for joint pain, high ANA and pericarditis.