I currently take 6 tablets a week and I started taking them in February this year . Has anyone been through the same as me, and find that the meds simply haven't worked so you have to simply start again. I have called my nurse specialist but she hasn't got back yet. Hang in there- it's very early days x I'm afraid Jacki08 is right it's early days and these meds take time. I am still in a lot of pain I have immense fatigue and feel miserable. I started MTX in September along with naproxen and gradually built up to 8 tablets (20mg) a week by the end of December. Can you abruptly stop hydroxychloroquine Withdrawal symptoms of plaquenil Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. Mar 24, 2011 no methotrexate doesn't always mean your hair will fall out or thin but some of the side effects are scary, but before you an progress onto other meds methotrexate is mandatory. for me methotreaxte and plaquenil does't work and i' intonate of sulfa so i am started embrel which states you have to have tried 2 of 3 meds and methotrexate is 1 of them. Jun 09, 2012 I have also tried hydroxychloroquine and sulfazalazine both of which caused tinnitus so had to come off them. My consultant has now put my methotrexate up to 25mg to see if my symptoms improve. I'm trying to stay positive but if this doesn't work what other treatment is there. it is so annoying as the combination of methotrexate and. Things have been in their stride since mid February and now it's looking good regarding fatigue, swelling and pain (though I only ever had a little pain compared to what others have described). I started taking mthx in October last year and expected results quite quickly. What if hydroxychloroquine doesn t work Early RA treatment - Hydroxychloroquine? Hi all, just., What next if plaquenil doesn't work? Aralen medicine pricePlaquenil somnolencePlaquenil immunoglobulin receptorMore energy on plaquenilHydroxychloroquine eye exam guidance ncbi Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Taking Plaquenil for Rheumatoid Arthritis. RA - what else can I try, now on methotrexate, have tried.. Hydroxychloroquine Uses, Dosage & Side Effects -. Does anyone take methotrexate and hydroxychloroquine and has anyone had problems with hydroxychloroquine. No joke I had to come off purely because I thought I was going to take off in work. Not good for credibility let me tell you xxxx Fi. Reply 0 Report. Hidden. in reply to Hidden. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. The typical dose for hydroxychloroquine is 200-400mg per day and is based on a person’s body weight or if you are overweight, your ideal body weight. Wrong Hydroxychloroquine Dose Is Common, Putting Eyes at Risk Up to half of patients treated with the arthritis drug hydroxychloroquine Plaquenil are prescribed more than the recommended maximum amount, according to new research.