Despite drastic containment measures, the spread of this virus is ongoing. SARS-Co V-2 is the aetiological agent of coronavirus disease 2019 (COVID-19) characterised by pulmonary infection in humans. Hydroxychloroquine dose based on weight and renal function Chloroquine phosphate tablets bp 250 mg Hydroxychloroquine sul 200 Plaquenil erosive arthritis Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. In rare cases, hydroxychloroquine Plaquenil can have side effects that affect the eyes, so people who take this medicine should see an ophthalmologist at least once a year. In the absence of a known efficient therapy and because of the situation of a public-health emergency, it made sense to investigate the possible effect of chloroquine/hydroxychloroquine against SARS-Co V-2 since this molecule was previously described as a potent inhibitor of most coronaviruses, including SARS-Co V-1. The efforts of international health authorities have since focused on rapid diagnosis and isolation of patients as well as the search for therapies able to counter the most severe effects of the disease. Effects of hydroxychloroquine RA and Hydroxychloroquine How Effective is it for Rheumatoid., Long-Term Side Effects of Plaquenil for Rheumatoid. Chloroquine trade name in egyptIncreasing plaquenil dose You may report side effects to Health Canada at 1-866-234-2345. PRECAUTIONS Before taking hydroxychloroquine, tell your doctor or pharmacist if you are allergic to it; or to other aminoquinolines e.g. chloroquine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects.. What are the side effects of hydroxychloroquine and.. Plaquenil Side Effects on Your Eyes and Vision. Fortunately, the problems seen by people taking this medication are usually very mild. Serious side effects are rare. Overall, most people who have any noticeable side effects from hydroxychloroquine experience diarrhea or nausea. These usually get better after the person adjusts to the medication. Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. Adverse effects. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. The most serious adverse effects affect the eye. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects.