I didn't seem to have any problems whatsoever with it initially, other than very short term and mild cramping/diarrhea. But now I've been dealing with considerable muscle aching and pain/spasm in some new places - or at least places that haven't bothered me in quite awhile. Hydroxychloroquine effects on blood sugar Plaquenil for scabbies Chloroquine method Muscle aches is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Pain. Polymyalgia rheumatica is a form of arthritis. It causes pain in the joints and muscles of the lower back, thighs, hips, neck, shoulder and upper arms, and other parts of the body. The condition occurs when the lining surrounding the joints, bursa and tendons near the shoulders and hips becomes inflamed. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. I felt the Plaquenil helped the fatigue, but it seems the pain is sabotaging that effect. My knees and legs hurt, back, hips, shoulders, fingers, and now my left heel - which has me limping half the time. Plaquenil and pain relief Plaquenil Uses, Dosage & Side Effects -, Polymyalgia Rheumatica Guide Causes, Symptoms and. Plaquenil lyme cystsBull's eye maculopathy hydroxychloroquineRetinal toxicity hydroxychloroquineChloroquine or proguanil Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil oral Reviews and User Ratings Effectiveness, Ease.. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil is prescribed as a disease-modifier, in other words, to decrease pain, decrease swelling, and prevent joint damage and disability. It is not known how Plaquenil works but researchers believe that Plaquenil interferes with communication between cells within the immune system. Ultimately, it is thought to block proinflammatory pathways. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin; Loss of appetite; Abdominal bloating; Upset stomach; Stomach cramps; Retinal damage – There is a small chance that retinal damage will occur while taking hydroxychloroquine Plaquenil or chloroquine Aralen.