Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Aao hydroxychloroquine guidelines Plaquenil and ibuprofen How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil increased appetite Abnormal Weight Gain and Gut Microbiota Modifications Are., Plaquenil Side Effects Common, Severe, Long Term - Chloroquine or mefloquine resistance malaria View detailed reports from patients taking Hydroxychloroquine Sulfate who experienced decreased appetite. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Hydroxychloroquine Sulfate Decreased Appetite Reports.. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Little appetite with plaquenil? lupi1109 posted I started to take plaquenil for my mild lupus about 3 weeks ago and I noticed that I am having less appetite these days. I get hungry during dinner time, but all the foods does not taste as good as before. It feels weird! Eating delicious food was one of the joy of my life. Increased thirst loss of appetite mood changes no pulse or blood pressure numbness or tingling in the hands, feet, or lips unconsciousness Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Started plaquenil about one week ago and have increased appetite ever since. I have spent some time looking into it and it's not associated with hormones or thyroid, it's definitely because of the plaquenil.