It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine phosphate chemical structure Hydroxychloroquine vs methotrexate for rheumatoid arthritis Despite all these benefits, hydroxychloroquine is too often still regarded as a second-line treatment, as we see from major randomised trials in which only about 50% of patients are treated with hydroxychloroquine, and even more strikingly from the absence of any mention of hydroxychloroquine in important studies. Aug 26, 2016 I have Lupus Nephritis and have had it for almost 12 years now. I strongly suggest you get tested for it because it sounds like that's what you may have, especially with protein in your urine. Better to be safe than sorry. I also take Plaquenil but it's stictly for my joints, all of my other medications are for my kidney function. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil and nephritis Nephritis - Wikipedia, Plaquenil side effects - kidney problems? - Symptoms - Life. Alopecia plaquenilPlaquenil scalp dandruffPlaquenil crest syndromeOcular side effects of chloroquine therapyIs coughing normal when taking plaquenil Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil Uses, Dosage & Side Effects -. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Lupus and Kidney Disease Lupus Nephritis NIDDK. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil is effective for Lupus patients, as well as people with UCTD described to me by a rheumatologist as "Lupus-like" or "Lupus-lite" or "mild Lupus". So it's very possible to be on Plaquenil without having a formal Lupus diagnosis. To get a Lupus diganosis you need to have 4 or more of 11 Lupus criteria, within a 5 year period. Non-adherence to lupus nephritis treatment is the most important factor for non-remission or renal relapses. Hydroxychloroquine HCQ is currently recommended long term for all patients with SLE provided no contraindications exist.