All my issues were resolved over a years time on low doses. I believe my problems started with side effects of a statin, which I stopped taking during my Plaquenil treatment but resumed after symptoms were resolved. Plaquenil kidneys Buy aralen 500mg Antimalarials are used in the treatment of dermatologic, rheumatic, and connective tissue diseases.1Chloroquine CQ toxicity is known to cause vacuolar myopathy and curvilinear body formation.2Hydroxychloroquine HCQ neuromyotoxicity is a rare complication characterized by proximal muscle weakness. Jun 25, 2013 I took Plaquenil for Sjogren's Syndrome. It got so I couldn't walk up a curb without help before I switched to oral Methotrexate. My peripheral neuropathy actually went away too, and my rheumy thinks it was a rare, toxic side-effect of the Plaquenil. I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. All my issues were resolved over a years time on low doses. I believe my problems started with side effects of a statin, which I stopped taking during my Plaquenil treatment but resumed after symptoms were resolved. Has anyone had neurological issues resolved with a Plaquenil treatment? I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. Years later I am now having small fiber issues in my hands which I think were triggered by side effect of statins and am looking for solutions. Hydroxychloroquine causing neuropathy Peripheral Neuropathy Causes The Foundation For., Hydroxychloroquine - thigh muscle weakness? Chloroquine philippinesHydroxychloroquine side effects retinopathy Peripheral neuropathy is found among people who take Plaquenil, especially for people who are female, 60+ old also take medication Methotrexate, and have High blood pressure. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated. Will you have Peripheral neuropathy with Plaquenil - eHealthMe. Plaquenil and small fiber neuropathy - NeuroTalk Support.. Risks of Hydroxychloroquine. Find information about common, infrequent and rare side effects of Hydroxychloroquine Oral. Medications that commonly cause rashes as side effects include gold Solganal, Myochrysine, methotrexate Rheumatrex, Trexall, leflunomide, and hydroxychloroquine Plaquenil. A rare, and serious, complication of rheumatoid arthritis is inflammation of blood vessels vasculitis, which can cause rash that most commonly appears in the fingertips, toes, or legs. Hydroxychloroquine is used in the treatment of various rheumatic conditions including systemic lupus erythematous. Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Here we report a case of woman with systemic lupus erythematosus who presented with myopathy after eight months treatment with hydroxychloroquine.