It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Methotrexate plaquenil and prednisone Side effects of long term use of plaquenil Describe eye tests for plaquenil Chloroquine and proguanil reviews If you take Plaquenil for your inflammatory disease, your ophthalmologist will check for damage to the retina in the back of the eye while you take the drug. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. To treat lupus erythematosus, the average adult dose is 400 mg once or twice daily. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. What does plaquenil do Protecting your eyesight when taking Plaquenil Lupus., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Hydroxychloroquine eye issuesPlaquenil and cancer Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders. Inflammatory Osteoarthritis And Plaquenil. Plaquenil Side Effects on Your Eyes and Vision. How Does Plaquenil Work For Rheumatoid Arthritis. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Hydroxychloroquine Plaquenil was originally used to treat malaria and is now used mostly to treat rheumatological and dermatological diseases. Its most frequent use now is for Rheumatoid Arthritis RA and Lupus and is often very effective in mitigating the joint and arthritic symptoms these diseases can cause. Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system.