In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Alternatives to hydroxychloroquine for arthritis Amaurosis fugax from plaquenil Can u stop taking plaquenil The estimated risk of hydroxychloroquine retinopathy in patients on chronic hydroxychloroquine therapy ranges from 0.4% to 8.0%. 1 Toxicity is thought to be dependent on cumulative total dose. 3 Additional factors that can precipitate early toxicity are concomitant renal disease and use of tamoxifen. 3 Figure 1. Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. A subtle case of hydroxychloroquine retinopathy spectral domain optical coherence tomography findings Skip to main content Thank you for visiting As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Oct findings with plaquenil toxicity Bull's-eye maculopathy due to hydroxychloroquine toxicity, My Take on New Ocular Screening Guidelines for Plaquenil. Para que sirve la hydroxychloroquine 200 mgPlaquenil arthritis medication Plaquenil Toxicity Condition/keywords plaquenil toxicity, hydroxychloroquine toxicity Imaging device Optical coherence tomography system Description SD-OCT scan from a 44-year-old woman with bilateral plaquenil toxicity. There is damage visible in the outer retina in a perifoveal distribution. Related files Plaquenil Toxicity - Retina Image Bank. A subtle case of hydroxychloroquine retinopathy spectral.. Plaquenil-Induced Toxic Maculopathy - Decision-Maker PLUS. Nov 01, 2015 SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. The most common side effect associated with its use is retinal toxicity. Ocular findings of HCQ retinal toxicity as detected by various screening modalities. A female patient was diagnosed with HCQ retinal toxicity at the age of 53 years, having taken HCQ for 12 years at 400 mg/day. Spectral domain optical coherence tomography as an effective screening test for hydroxychloroquine retinopathy the “flying saucer” sign Eric Chen, David M Brown, Matthew S Benz. Although no other clinical or ancillary testing was able to detect toxicity in this patient, SD OCT findings helped confirm HVF findings. These SD OCT.