It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil saved my life Does plaquenil help restore hair loss Hydroxychloroquine treatment myalgia Nifedipine and hydroxychloroquine Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. Objective To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine is an antimalarial medication that can cause hyperpigmentation of nails, mucosa, and skin 1–5. Retrospective studies cite the incidence of drug-related hyperpigmentation from hydroxychloroquine to be as high as 33% of individuals. Elder abuse is a cause of significant morbidity and mortality in older individuals 7–9. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil induced bruising on shins Plaquenil Side Effects Common, Severe, Long Term -, Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Chloroquine autophagy micePharmacological treatment with chloroquine inhibits autophagy in vivoHydroxychloroquine eye damage Our data support the hypothesis that hydroxychloroquine-induced pigmentation is secondary to ecchymosis or bruising. OBJECTIVE To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Hydroxychloroquine-induced pigmentation in patients with.. Hydroxychloroquine-Associated Hyperpigmentation. - PubMed Central PMC. Has anyone taking Plaquenil ever experienced bruising under.. WebMD's guide to the symptoms of lupus. When you have lupus, something happens to your body’s natural defense system your immune system to make it work incorrectly. Instead of only targeting. Immune thrombocytopenia ITP is a disorder that can lead to easy or excessive bruising and bleeding. The bleeding results from unusually low levels of platelets — the cells that help blood clot. Formerly known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises, as well as tiny reddish-purple dots that look like a rash. The long-term use of hydroxychloroquine in systemic lupus erythematosus treatment is associated with skin lesions in about 7%–29% of the patients.1 2 It usually involves the oral mucosa, shins, nails, forearms and anterior side of the legs.1 2 The time of onset ranges from few months to years after starting treatment, opposite to the ophthalmological adverse effects that are associated with.