Please set your browser to accept cookies to continue. This cookie stores just a session ID; no other information is captured. Hydroxychloroquin and methotrexate Acute chloroquine poisoning Chloroquine lethal dose Adverse reaction to plaquenil The patients were treated with methotrexate alone, the combination of hydroxychloroquine and sulfasalazine, or all three drugs. They received methotrexate Rheumatrex, Lederle, Pearl River, N. Y. or placebo in one bottle, sulfasalazine Azulfidine, Pharmacia, Columbus, Ohio or placebo in another bottle. Hydroxychloroquine is sometimes combined with methotrexate for additive benefits for signs and symptoms or as part of a regimen of “triple therapy” with methotrexate and sulfasalazine. Mechanism The mechanism of action of antimalarials in the treatment of patients with rheumatoid arthritis is unknown but is thought to involve changes in antigen presentation or effects on the innate immune system. Sulfasalazine Remove Sulfasalazine from your drug comparison Add another drug to compare View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more. Hi everyone, My Rheumatologist told me he has to take me off of Prednisone and wants to start me on another RX. My choices are Methotrexate, Plaquenil or Sulfasalzine (Azulfidine). Accepting the NEJM cookie is necessary to use the website. Compare sulfasalazine to plaquenil Compare Plaquenil vs Sulfasalazine vs Remicade vs. - Iodine, Rheumatoid Arthritis Treatment Options Johns Hopkins. Plaquenil for ivfChloroquine dosing for ophthalmologyChloroquine regimenAlternatives to hydroxychloroquine for arthritisHydroxychloroquine discontinue I was dx in August with Lupus and my Rheumy said she was afraid to start me on Plaquenil since I had a bad reaction to a Sulfa antibiotic I took and the same reaction when a Dr gave me Lasix. I read that the sulfa in Plaquenil is different from those in antibiotics and most people with Lupus have an allergy to Sulfa but can take Plaquenil. Plaquenil and Sulfa Allergies" Lupus Community - Support.. Methotrexate vs Sulfasalazine Comparison -. Plaquenil hydroxychloroquine sulfate dose, indications.. This guide summarizes evidence comparing the effectiveness and safety of disease-modifying antirheumatic drugs DMARDs and corticosteroids used for rheumatoid arthritis RA. It does not address other drugs that are no longer commonly used as first-line treatment for RA, such as azathioprine, chloroquine, cyclosporine, gold, and penicillamine. Plaquenil vs Methotrexate I was diagnosed with RA a month ago and am returning to my Rheumatologist tomorrow to discuss treatment options. The doctor said that given where I am right now constant low level pain and light swelling of my hands and wrists but no joint damage showing up on xrays or the ultrasound, she gave me a choice of starting. Sulfasalazine may cause blood problems. These problems may result in a greater chance of certain infections, slow healing, and bleeding of the gums. Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. Dental work should be delayed until your blood counts have returned to normal.