The main finding in scleroderma is thickening and tightening of the skin and inflammation and scarring of many body parts, leading to problems in the lungs, kidneys, heart, intestinal system and other areas. Twins and family members of those with scleroderma or other autoimmune connective tissue diseases, such as lupus, may have a slightly higher risk of getting scleroderma. There is still no cure for scleroderma, but effective treatments for some forms of the disease are available. Children can also develop scleroderma, but the disease is different in children than in adults. Plaquenil tb risk Chloroquine cytotoxic hemozoin falicparum But the clear link between tryptophan and eosinophilia myalgia syndrome and the scleroderma-like disease associated with contaminated rapeseed oil ingestion raise the possibility that exposure to something in the environment could trigger scleroderma. Symptoms. The symptoms of scleroderma vary from person to person and can include For months now my skin has been thickening I have now reached the point where I feel as though my arms are going to split like a sausage and been extremely inflamed and painful. A month ago I started on Plaquenil and prednisolone. It has helped a bit with the inflammation but on reading various. Long term ratings 3/5. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Systemic sclerosis scleroderma and for what kind of people. The study is created by eHealthMe from 11 Plaquenil users and is updated continuously. eHealthMe has been monitoring drugs and supplements since 2008. A great deal of research is also underway to find better treatments for scleroderma and, hopefully, someday a cure. Although the underlying cause is unknown, promising research is shedding light on the relationship between the immune system and scleroderma. Hydroxychloroquine for crest syndrome Methotrexate in Patients With Scleroderma/CREST Syndrome, Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums Plaquenil price in uaeDosage of plaquenil for rheumatoid arthritis I stopped Plaquenil eons ago prior to Cytokine testing and haven't needed to get back on it. While it is a good drug, it is a good drug for what it's indicated for and CREST syndrome, lupus, Sjogrens and other auto-immune conditions will benefit from it. As a reminder it will only work if taken over the long term. Plaquenil/ hydroxychloroquine Phoenix Rising ME / CFS Forums. How effective is Plaquenil for Systemic sclerosis.. Common "Crest Syndrome" queries answered by top doctors iCliniq. An estimated 25 to 40 percent of those with CREST syndrome will develop calcinosis cutis after 10 years. The lesions usually appear around fingers and elbows and may break open and leak a thick. CREST Syndrome and Scleroderma Some people have a type of scleroderma called CREST syndrome or limited scleroderma. Unlike other types, which only affect the arms, legs, and face, this kind can. This section of the Scleroderma FAQ is focused on standard treatment approaches that are designed either to target the overall disease process or to modify the disease in a way that can potentially improve more than one symptom, for example, bosentan Tracleer for skin ulcers and PAH.