Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil and grapefruit Can glucose and bind to chloroquine Seronegativera plaquenil Hydroxychloroquine Screening You have been invited to attend a Hydroxychloroquine Screening appointment at the Eye Treatment centre at the West Suffolk Hospital. Good question. Back on nov 5 i think it was i felt there was a really good discussion about hydroxychlorouine & eye tests here. One of us posted detailed info about her experience & the different types of eye test anyone on plaquenil etc would probably be best to have, and the frequency. Eye care specialists provide a valuable service when screening for Plaquenil retinal toxicity and advising the treating physician or rheumatologist with regards to the patient’s risk, safe dosing and appropriate screening procedures. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Eye screening for plaquenil Despite Plaquenil dosing recommendations, retinal toxicity., Plaquenil/Hydroxychloroquine - which eye tests do. - LUPUS UK Hydroxychloroquine lyme diseasePlaquenil cardiac Disease EntityDiagnosisManagementAdditional ResourcesReferences Hydroxychloroquine toxicity - EyeWiki. How to Succeed in Plaquenil Screenings. Revised recommendations on screening for chloroquine and.. TELL YOUR DOCTOR. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis, prevent joint damage and reduce the risk of long- term disability. Jan 18, 2019 Hydroxychloroquine Plaquenil was originally used to treat malaria and is now used mostly to treat rheumatological and dermatological diseases. Its most frequent use now is for Rheumatoid Arthritis RA and Lupus and is often very effective in mitigating the joint and arthritic symptoms these diseases can cause. Jun 13, 2019 If you take Plaquenil for your inflammatory disease, your ophthalmologist will check for damage to the retina in the back of the eye while you take the drug.