Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Psoriasis and plaquenil Glioblastoma chloroquine Hydroxychloroquine plaquenil oitcome for lupas patients Mechanism of action. Chloroquine appears to work via multiple mechanisms, including Interference with with the cellular receptor ACE2 potentially making it particularly effective against SARS and COVID-19. Impairment of acidification of endosomes, which interferes with virus trafficking within cells. Chloroquine is an antimalarial drug. It is also used for other medical conditions. It is not exactly known how its mechanism of action works but it is suspected to inhibit certain enzymes from its interaction with DNA. Chloroquine Clinical Indications. Chloroquine was originally made for the treatment of malaria. Chloroquine Mechanism of action and resistance in malaria 2 minutes Microbiology Chloroquine is also used to treat amebiasis (infection caused by amoebae). Chloroquine is used to treat and to prevent malaria. What is the mode of action of chloroquine Aralen chloroquine Malaria Drug Side Effects & Dosage, Chloroquine or Hydroxychloroquine Plaquenil and the Ocular Effects Can plaquenil cause dry mouthHow long for plaquenil to take effect A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Chloroquine Indications, Side Effects, Warnings -. Chloroquine Mechanism of action and resistance in malaria 2.. Chloroquine Mode of Action Science. Mechanism of Action Chloroquine is an antimalarial agent. While the drug can inhibit certain enzymes, its effect is believed to result, at least in part, from its interaction with DNA. Chloroquine is an anti- malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. An important mode of action of chloroquine and hydroxychloroquine is the interference of lysosomal activity and autophagy.