It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Can you take plaquenil at night Can plaquenil treat psoriasis Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced. Hydroxychloroquine does take a while to take effect. Arthritis UK gives a figure of around 12 weeks, whilst the American College of Rheumatology says, "symptoms can start to improve after 1-2 months, but it may take up to 6 months before the full benefits are felt". My own rheumy said, "3-4 months". With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long does it take plaquenil to start working LUPUS MEDICINES, How long until Hydroxychloroquine takes effect - LUPUS UK Should i stop taking plaquenil if i have kidney problemsCan i take a multivitamin with plaquenilPlaquenil kidney problemsSarafen and plaquenil Rw856 My rheumatologist said hydroxychloroquine can take up to three months to work. I'd been on it just over two months before it started to make a difference 200mg morning only. But then a few weeks after that I started on antibiotics and now it doesn't seem to be working as well! How long does hydroxychloroquine take. - St Thomas Lupus T.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. How long does plaquenil hydroxychloroquine take. - HealthTap. For women, start with 100 pounds, and add 5 pounds for every inch over 5 feet. For men, start with 106 pounds, and add 6 pounds for every inch over 5 feet. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. Depending on how full your stomach it codine should take 20 min to a hour to work. If you are taking hydroxychloroquine over a long duration, it is important to take eye exams every 6 to 12 months. 6 Do not take hydroxychloroquine if you experience vision symptoms, including problems seeing or reading, light sensitivity, blurred distance vision, or light flashes or streaks.