Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine diphosphate salt What class of drugs is hydroxychloroquine H-chloroquine side effects Hydroxychloroquine also known as Hearing loss is more strongly associated with Sjogren's than with lupus or RA, but can happen. I recall that Plaquenil is associated with hearing loss so your doc has to consider whether it's a totally unrelated to either, b related to your lupus, c related to your medications, or d a combination of both. Plaquenil medication reduces skin problems in lupus and prevents swelling or pain in arthritis. However, it is still not known exactly how the drug works. Side Effects. Just like any other medication, Plaquenil also has few side effects. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Does hearing loss from plaquenil come back Does Plaquenil cause Hearing Loss? - Treato, Common Side Effects of Plaquenil Taking hydroxychloroquine for lupusPlaquenil rp It took me one year to get diagnosed, but I probably had it for almost 10 years prior to that. I had been having so many symptoms and had been sick off and on since 1985. It all started with back to back horrendous sinus infections and went downhill from there. Plaquenil is working.does that mean.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hearing loss. Has anyone taking Plaquenil. - LUPUS UK. I don't know for sure if it is the plaquenil or other meds but my rheumy seems to have my inflammation/stiffness under pretty good control. Been taking plaquenil and arava for about a year. Just rediced plaquenil from one tablet twice a day to one tablet once a day. I also take Cimzia injections bi-weekly but that has only been for about 6 months. I find that when The lupus is more flared in my body is when the tinnitus is more prevalent. At times I don't hear it or I'm not aware of it, we need to be rementioning this more to our rheumatologist. They are not so quick to put 2 + 2 together with hydroxychloroquine and tinnitus – hearing loss to follow. Growing Back that Gorgeous Head of Hair. I was on Plaquenil in the past for joint problems and liked it. I didn't notice any other side effects, but hearing of sight loss scares me as I am looking to go back on them. I think I will be experimenting w MSM a little more before turning to Plaquenil. Hope this is helpful.