It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil cause insomnia Retinal changes with the use of hydroxychloroquine Chloroquine zika nature Systemic sclerosis SSc such as limited or diffuse scleroderma, can cause hyperpigmentation darkening and hypopigmention lightening of the skin, usually in the areas which have been affected by skin hardening. Hydroxychloroquine is one of several antimalarial drugs that have anti-inflammatory effects useful in other diseases. It is licensed in the UK for the treatment of malaria. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. Objective To describe the clinical features and outcome of hydroxychloroquine HCQ-induced pigmentation in patients with systemic lupus erythematosus SLE. Design, Setting, and Participants In a case-control study conducted at a French referral center for SLE and antiphospholipid syndrome, 24 patients with SLE. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine skin darkening Hydroxychloroquine-related skin discoloration CMAJ, Hydroxychloroquine Skin Support What will happen if i stop taking plaquenilHydroxychloroquine hyperpigmentation Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Hydroxychloroquine-Induced Pigmentation in Patients With.. Plaquenil and skin discoloration - Sjogren's World. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong.